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CASE REPORT
Year : 2014  |  Volume : 6  |  Issue : 3  |  Page : 264-266

Recurrent dermatomyositis manifesting as a sign of recurrent transitional cell carcinoma of urinary bladder: Long-term survival


1 Department of Urology, Ninewells Hospital (NHS Tayside), Medical School, Medical Research Institute, University of Dundee, Dundee, Scotland (UK), DD1 9SY
2 Department of Pathology, Royal Infirmary of Edinburgh (NHS Lothian), 51 Little France Crescent, Edinburgh EH16 4SA, Scotland
3 Department of Pathology, Ninewells Hospital (NHS Tayside), Medical School, Medical Research Institute, University of Dundee, Dundee, Scotland (UK), DD1 9SY
4 Department of Radiation Oncology, Ninewells Hospital (NHS Tayside), Medical School, Medical Research Institute, University of Dundee, Dundee, Scotland (UK), DD1 9SY

Correspondence Address:
Ghulam Nabi
Senior Clinical Lecturer in Surgical Uro oncology, Consultant Urological Surgeon, Medical Research Institute, Ninewells Hospital and Medical School, Dundee, Scotland, UK

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DOI: 10.4103/0974-7796.134299

PMID: 25125907

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The association between urological malignancies and paraneoplastic syndromes has been well documented. We report a case of recurrent dermatomyositis manifesting as a sign of metastatic recurrence of non-muscle-invasive transitional cell carcinoma of the bladder, a relationship which has only been referred to in a few reports. The case highlights a few important clinical challenges; firstly, the importance of thorough investigation for underlying malignancy in patients with dermatomyositis, as successful treatment of such malignancy can lead to resolution of paraneoplastic symptoms, and secondly, a high index of suspicion of recurrence in cases where paraneoplastic manifestations recur. Metastatic pulmonary recurrence without local evidence of disease at a follow-up of 4 years makes this case unique. Moreover, in the light of our experience and reported literature, a framework is suggested to approach such a diagnostic dilemma in the future. Description of the case will guide clinicians in the future, in case they encounter such an unusual clinical scenario. This could also serve as a hypothesis-generating source for designing future research as well.


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