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Table of Contents
CASE REPORT
Year : 2020  |  Volume : 12  |  Issue : 2  |  Page : 184-186  

Giant pancreatic mucinous cystadenoma masquerading as renal hydatid disease


Department of Urology, MIOT International, Chennai, Tamil Nadu, India

Date of Submission06-Apr-2019
Date of Acceptance24-Dec-2019
Date of Web Publication14-Apr-2020

Correspondence Address:
Dr. Shanmugasundaram Rajaian
Department of Urology, MIOT International, 4/112, Mount Poonamallee Road, Manapakkam, Chennai - 600 089, Tamil Nadu
India
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DOI: 10.4103/UA.UA_51_19

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   Abstract 

Mucinous cystic neoplasms of the pancreas are the most common pancreatic cystic neoplasms. A 54-year-old female presented with an abdominal mass and was diagnosed to have a multilocular hydatid cyst from the left kidney by imaging. During surgery, a large thick-walled cyst with multiple loculi was seen arising from the upper pole of the left kidney and adherent to the distal pancreas and splenic vessels. The cyst was completely excised without hilar clamping. Histopathological examination confirmed mucinous cystadenoma arising from the pancreas. In conclusion, imaging can be unreliable in differentiating benign renal cysts from tumors of adjacent organs, raising a diagnostic dilemma. Surgical excision only would be able to differentiate the conditions as in our case.

Keywords: Hydatid cyst, mucinous cystic neoplasms, pancreas, renal cyst


How to cite this article:
Rajaian S, Paulraj AS, Murugesan L, Sengottaiyan P. Giant pancreatic mucinous cystadenoma masquerading as renal hydatid disease. Urol Ann 2020;12:184-6

How to cite this URL:
Rajaian S, Paulraj AS, Murugesan L, Sengottaiyan P. Giant pancreatic mucinous cystadenoma masquerading as renal hydatid disease. Urol Ann [serial online] 2020 [cited 2020 Jul 7];12:184-6. Available from: http://www.urologyannals.com/text.asp?2020/12/2/184/282399




   Introduction Top


Renal cystic lesions are often classified as benign or malignant based on imaging characteristics. Using the current diagnostic imaging techniques, it is difficult to differentiate renal neoplasms from essentially benign conditions without malignant potential. Here, we report an interesting case of giant pancreatic mucinous cystadenoma masquerading as renal hydatid disease.


   Case Report Top


A 54-year-old female presented with diffuse fullness of the abdomen for the past 3 months. Her past history was significant for exposure to multiple pet animals. Her examination revealed an ill-defined mass in the left upper abdominal quadrant. An abdominal contrast-enhanced computed tomography scan showed a multiseptated exophytic cystic lesion of 18 cm × 10 cm × 16 cm size from the upper pole of the left kidney displacing the spleen and pancreas. Magnetic resonance imaging abdomen showed an exophytic multicystic heterogenous hyperintense T2-weighted and hypointense T1-weighted lesion with thin hypointense internal septae seen arising from the superior pole of the left kidney [Figure 1]. Indirect hemagglutination test and enzyme-linked immunosorbent assay were negative. A diagnosis of multilocular renal cyst or renal hydatid cyst was made based on the imaging and planned for excision.
Figure 1: (a-c) Axial and coronal T1- and T2-weighted fat-saturated magnetic resonance imaging images showing well-circumscribed heterogeneous hyperintense lesion with hypointense septae (hollow arrows) arising from the upper pole of the left kidney displacing the pancreas and splenic vessels (white solid arrow)

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Oral albendazole (400 mg twice a day) was started for 2 weeks before surgery. Under general anesthesia, chevron incision was made and abdominal exploration was done. The left colon was reflected medially. A large dumbbell-shaped thick-walled cyst of size 18 cm × 12 cm × 12 cm with multiple loculi seen attached to the upper pole of the left kidney and was adherent to the distal pancreas and splenic vessels. On aspiration, thick mucoid straw-colored material was aspirated out. Scolicidal agent (5% povidone-iodine) was instilled. Renal vessels were dissected out and looped [Figure 2]a. Renal vessels were not clamped during the excision of the cystic lesion as the cyst wall had less vascularity and its margins were well delineated. The splenic vessels and distal pancreas were carefully dissected and preserved. The cyst was completely excised [Figure 2]b with a margin of renal tissue. The collecting system in the upper pole of the left kidney was not entered, and it was confirmed by intraoperative injection of methylene blue through a previously placed ureteric catheter in the renal pelvis. A tube drain was placed intraoperatively and removed on the 4th postoperative day. On gross examination, the cyst was a thick-walled, multilocular cyst with a dominant loculus and no brood capsules were found. Microscopic examination revealed the features of mucinous cystadenoma arising from the pancreas [Figure 3]. The patient had an uneventful recovery.
Figure 2: Renal vessels were dissected out and looped (a). Splenic vessels and distal pancreas were carefully dissected and preserved (black hollow arrow). The cyst was completely excised (b) with a margin of renal tissue (white hollow arrow)

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Figure 3: (a and b) Cystic tumor lined by a single layer of tall mucinous columnar epithelium (black hollow arrow) (H and E, ×40) (c) The fibrous stroma shows several foci of pancreatic tissue with lobules of pancreatic acini (black hollow arrow) (H and E, ×100)

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   Discussion Top


Mucinous cystic neoplasms of the pancreas are the most common pancreatic cystic neoplasms and account for around half of the cases. They are commonly seen in women. The present case demonstrates challenges in the confirmed preoperative diagnosis of mucinous cystic neoplasm of the pancreas. In this case, radiographic examination showed a large cyst arising from the upper pole of the left kidney leading to the diagnosis of multilocular renal cyst or renal hydatid cyst.

Although renal hydatid cyst is relatively uncommon in India, it accounts for around 2% of cases.[1] In addition, there are several reports of pancreatic hydatid cyst masquerading as cystic pancreatic neoplasm.[2],[3],[4] Sometimes, it is challenging to diagnose cystic neoplasm of pancreas preoperatively based on radiological findings when the lesion is closely associated to the upper pole of the left kidney.

Mucinous cystic neoplasms have been extensively described in the pancreas, appendix, lung, breasts, and spleen. However, when they overlap with other organs, it may be difficult to get a correct preoperative diagnosis. To our knowledge, this is the first case report where a large pancreatic mucinous cystadenoma masquerading as renal hydatid disease. Considering the differential diagnosis of renal hydatid cyst, oral albendazole was started before the surgery.

In conclusion, Imaging can be unreliable in differentiating benign renal cysts from tumors of adjacent organs, raising a diagnostic dilemma. Surgical exploration and excision are required to reliably establish the etiology of the lesion. A benign pancreatic cystic neoplasm has to be considered as a differential diagnosis during the evaluation and management of giant renal cystic lesions, diagnosed by imaging.

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
   References Top

1.
Ramteke VV, Deshpande NS, Balwani MR, Bawankule CP. Primary renal echinococcosis. Indian J Nephrol 2017;27:316-8.  Back to cited text no. 1
[PUBMED]  [Full text]  
2.
Wadhwa N, Chauhan U, Agrawal S, Nischal N, Puri SK. Pancreatic head hydatid cyst masquerading cystic pancreatic neoplasm in a young female. J Clin Diagn Res 2017;11:TD01-3.  Back to cited text no. 2
    
3.
Reddy VV, Sivaramakrishna G, Chandramaliteeeswaran C, Sarala S, Rukmangada N. Pancreatic hydatid masquerading as cystic neoplasm. J Surg Operative Care 2018;3:1-3.  Back to cited text no. 3
    
4.
Bansal VK, Misra MC, Krishna A, Kumar S, Garg P, Khan RN, et al. Pancreatic hydatid cyst masquerading as cystic neoplasm of pancreas. Trop Gastroenterol 2010;31:335-7.  Back to cited text no. 4
    


    Figures

  [Figure 1], [Figure 2], [Figure 3]



 

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