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  Indian J Med Microbiol
 

Figure 1: Schematic representation of free cytosolic calcium: (1) Adrenergic nerve fi ber endings and (2) endothelial cells release norepinephrine, endothelins, and PGF2á, which lead to initiate the cascade of reactions that eventually result in elevation of free cytosolic Ca++ concentrations. (3) Voltage-gated calcium channels are another source of free cytosolic calcium that lead to an increase in the level of free cytosolic Ca++ due to an influx of extracellular calcium. Voltage-gated calcium channels in the nerve fi bers are thought to aid in depolarization leading to the release of neurotransmitters

Figure 1: Schematic representation of free cytosolic calcium: (1) Adrenergic nerve fi ber endings and (2) endothelial cells release norepinephrine, endothelins, and PGF2á, which lead to initiate the cascade of reactions that eventually result in elevation of free cytosolic Ca++ concentrations. (3) Voltage-gated calcium channels are another source of free cytosolic calcium that lead to an increase in the level of free cytosolic Ca++ due to an influx of extracellular calcium. Voltage-gated calcium channels in the nerve fi bers are thought to aid in depolarization leading to the release of neurotransmitters