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Year : 2012  |  Volume : 4  |  Issue : 1  |  Page : 45-47

Lymphoepithelioma-like carcinoma of the urinary bladder: A case report and review of systemic treatment options

1 Department of Urology, Charing Cross Hospital, London, United Kingdom
2 Department of Clinical Oncology, Charing Cross Hospital, London, United Kingdom
3 Department of Pathology, Charing Cross Hospital, London, United Kingdom

Correspondence Address:
Nicholas M Pantelides
48 St Clements Mansions, Lillie Road, London SW67PQ
United Kingdom
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DOI: 10.4103/0974-7796.91626

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Lymphoepithelioma-like carcinoma (LELC) of the urinary bladder is a rare variant, which can occur in a pure form or in conjunction with transitional cell carcinoma. Owing to the scarcity of reported cases, the optimum treatment is yet to be defined, although the benefits of chemotherapy are increasingly recognised. We present a case of a 64-year-old man with pure LELC, treated with trans-urethral resection of the bladder tumor (TURBT) and primary gemcitabine and platinum-based chemotherapy. He remained free of disease at six-month follow-up cystoscopy. The case adds to the growing evidence for the efficacy of chemotherapy, coupled with TUR, as part of a bladder-preserving treatment option for LELC.

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