Urology Annals
About UA | Search | Ahead of print | Current Issue | Archives | Instructions | Online submissionLogin 
Urology Annals
  Editorial Board | Subscribe | Advertise | Contact
Users Online: 647   Home Print this page  Email this page Small font size Default font size Increase font size

Table of Contents
Year : 2012  |  Volume : 4  |  Issue : 3  |  Page : 195  

Urinary pH, melamine, and kidney stone formation

Wiwanitkit House, Bangkhae, Bangkok, Thailand

Date of Web Publication18-Oct-2012

Correspondence Address:
Somsri Wiwanitkit
Wiwanitkit House, Bangkhae, Bangkok, Thailand 10160
Login to access the Email id

DOI: 10.4103/0974-7796.102678

PMID: 23248531

Rights and Permissions

How to cite this article:
Wiwanitkit S, Wiwanitkit V. Urinary pH, melamine, and kidney stone formation. Urol Ann 2012;4:195

How to cite this URL:
Wiwanitkit S, Wiwanitkit V. Urinary pH, melamine, and kidney stone formation. Urol Ann [serial online] 2012 [cited 2021 Sep 23];4:195. Available from: https://www.urologyannals.com/text.asp?2012/4/3/195/102678


A recent publication on urinary pH, melamine, and kidney stone formation is very interesting. [1] Lu et al. reported "an association of gender and urinary pH with melamine-associated kidney stone formation risk". [1] This can be useful epidemiological information. However, some facts of medical biochemistry should be discussed. The reported pH in this publication is not clear. Only a value of < and ≥6.5 can be read. Indeed, the correlation can be directly assessed by the correlation study between the exact urine pH value and solubility. Based on chemical structure, melamine is a base and increases solubility in acidic conditions (very good if pH is lower than 4). [2] However, it is a fact that the range of human urine pH is not wide (4.5-8); hence, the solubility of melamine might be affected slightly.

   References Top

1.Lu X, Wang J, Cao X, Li M, Xiao C, Yasui T, et al. Gender and urinary pH affect melamine-associated kidney stone formation risk. Urol Ann 2011;3:71-4.  Back to cited text no. 1
[PUBMED]  Medknow Journal  
2.WHO. Background Paper on the Chemistry of Melamine Alone and in Combination with Related Compounds. Available online at www.who.int/entity/foodsafety/fs_management/Melamine_2.pdf.  Back to cited text no. 2


    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Access Statistics
    Email Alert *
    Add to My List *
* Registration required (free)  

  In this article

 Article Access Statistics
    PDF Downloaded343    
    Comments [Add]    

Recommend this journal