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Year : 2014  |  Volume : 6  |  Issue : 4  |  Page : 381-383

A bone fide atypical fibroxanthoma of penis

1 Deparment of Medicine and Surgery, University of Salerno, Italy
2 Unit of Pathologic Anatomy, ASL Salerno, Hospital Scarlato, Scafati, Italy
3 Department of Pathologic Anatomy, A. O. U. S. Giovanni and Ruggi D' Aragona, Salerno, Italy

Correspondence Address:
Antonio D'Antonio
Unit of Pathologic Anatomy, A. O. "San Giovanni di Dio e Ruggi d'Aragona" via S. Leonardo, Salerno
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DOI: 10.4103/0974-7796.141009

PMID: 25371625

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Malignant mesenchymal tumors of the penis are very rare and they have vascular origin. We present a case of a 71-year-old man with a painless nodule of 2.0 cm in diameter located in the penile foreskin. There was no history of urinary or sexually transmitted disease. An excisional biopsy revealed a markedly pleomorphic sarcoma resembling atypical fibroxanthoma (AFX) associated with a squamous cell carcinoma in situ. The patient refused a wide re-excision and was free of disease after 36 months. Because the different therapeutic management and prognosis, differential diagnosis should be made with sarcomatoid squamous cell carcinoma and melanoma: A diagnosis of AFX or malignant fibrous histiocytoma may be considered only after the complete exclusion of these two entities.

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