| ORIGINAL ARTICLE |
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| Year : 2021 | Volume
: 13
| Issue : 1 | Page : 36-40 |
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Single-dose instillation of povidone iodine for chyluria: A safe and effective therapy
Praveen Kumar Yadav, Samir Swain, Anunay Singh, Arshad Hasan, Md Faizul Haque, Gaurab Kundu, Bhupendra Kumar Sharma, Datteswar Hota
Department of Urology, SCB Medical College and Hospital, Cuttack, Odisha, India
Correspondence Address:
Dr. Samir Swain
Department of Urology, SCB Medical College and Hospital, Cuttack, Odisha
India
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DOI: 10.4103/UA.UA_159_19 
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Introduction: Management of chyluria with initial conservative approach and then using endoscopic sclerotherapy is a mainstay approach. However, a wide range of sclerosants are available with differential success rates and complication rates. This study evaluated the safety and efficacy of a single-dose instillation of 1% povidone iodine for the treatment of chyluria.
Materials and Methods: This was a prospective, observational study conducted on patients with chyluria who did not respond to conservative management with dietary restriction and diethylcarbamazine. The site of chyle efflux was identified by cystoscopy. A 6 Fr ureteral stent was inserted into effluxing side, diluted contrast was injected to delineate the pelvicalyceal system and the pyelolymphatic connection (arborization of the pelvicalyceal system), and a single-dose of 1% povidone iodine was instilled. Patients were observed for loin pain, fever, and disappearance of milky urine postinstillation and followed up at intervals of 3 months for a total duration of 1 year.
Results: Of a total 50 patients included, 35 were men and 15 were women, with a mean age of 37 years. Pyelolymphatic connections were noted in 48% of the patients. All patients showed an immediate disappearance of milky urine. During 1-year follow-up, 92% of the patients were symptom-free till the last follow-up while only 8% of the patients experienced recurrence of chyluria which were treated with other treatment modalities. The mean duration of recurrence was 8 weeks.
Conclusion: Single dose of 1% povidone iodine was effective in immediate clearance of milky urine and well tolerated in patients with chyluria during 1-year follow-up.
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