Year : 2016 | Volume
: 8 | Issue : 2 | Page : 203--207
Deep sedation in GreenLight laser prostatectomy
Fotini Fligou1, Panagiotis Kallidonis2, Nicolaos Flaris1, Abdulrahman Al-Aown3, Iason Kyriazis2, Marinos Vasilas2, Vasilis Panagopoulos2, Petros Perimenis2, Evangelos Liatsikos2, Theofanis Vrettos1
1 Department of Anesthesiology, University of Patras, Greece
2 Department of Urology, University of Patras, Greece
3 Department of Urology, Armed Forces Hospital Southern Region, Khamis Mushait, Saudi Arabia
Introduction: Evaluation of ketamine and propofol combination for the performance of photoselective vaporization of prostate (PVP).
Patients and Methods: Twenty-six patients undergoing PVP for benign prostatic hyperplasia were included in the study. Co-morbidities were present in 24 patients. Midazolam 2 mg intravenous was administered for the induction to anesthesia. Propofol (10 mg/ml) and ketamine (1 mg/ml) were administered with the use of two pumps. An initial bolus dose of 0.03 ml/kg of propofol and 5 mg of ketamine was administered intravenously. The anesthesia was maintained by continuous infusion of 0.01 ml/kg/min of propofol and 2 ml/min of ketamine. Fentanyl was administered when deemed necessary. The level of sedation, peri-operative parameters and side-effects were recorded.
Results: The average periods from the induction of anesthesia and intraoperative infusion were 12.38 ± 5.84 min and 59.5 ± 22.15 min, respectively. Average propofol and total ketamine dose were 85.5 ± 10.62 μg/kg/min and 144.9 ± 45.62 mg, respectively. The average dose of fentanyl administered was 29.81 ± 27.40 μcg. An average period between the end of the infusion and the discharge to the urology clinic was 34.62 ± 22.89 min. Ten patients experienced nausea and five eventually vomited. Hallucinations were observed in five cases while visual disturbances in two patients.
Conclusion: The combined use of ketamine and propofol for the performance of PVP proved to be an efficient method for anesthesia. The “deep sedation” provided by these drugs was not associated with significant side-effects. Moreover, the use of the above method is indicated in patients with significant co-morbidities that should undergo PVP.
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|How to cite this article:|
Fligou F, Kallidonis P, Flaris N, Al-Aown A, Kyriazis I, Vasilas M, Panagopoulos V, Perimenis P, Liatsikos E, Vrettos T. Deep sedation in GreenLight laser prostatectomy.Urol Ann 2016;8:203-207
|How to cite this URL:|
Fligou F, Kallidonis P, Flaris N, Al-Aown A, Kyriazis I, Vasilas M, Panagopoulos V, Perimenis P, Liatsikos E, Vrettos T. Deep sedation in GreenLight laser prostatectomy. Urol Ann [serial online] 2016 [cited 2021 Oct 25 ];8:203-207
Available from: https://www.urologyannals.com/article.asp?issn=0974-7796;year=2016;volume=8;issue=2;spage=203;epage=207;aulast=Fligou;type=0