Urology Annals

ORIGINAL ARTICLE
Year
: 2020  |  Volume : 12  |  Issue : 2  |  Page : 144--149

Correlation of metabolic syndrome and urolithiasis: A prospective cross-sectional study


Keerthi Rams, S Joseph Philipraj, Rohit Purwar, Balabhaskar Reddy 
 Department of Urology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth, Puducherry, India

Correspondence Address:
Dr. S Joseph Philipraj
Department of Urology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth, Puducherry
India

Background: Correlation between urolithiasis and metabolic syndrome has been demonstrated in the literature. This study assessed the association of metabolic syndrome and its components with urolithiasis in Indian patients. Methods: A cross-sectional prospective observation study included patients aged >18 years with urolithiasis. Demographic details, body mass index (BMI), waist circumference, blood pressure, and laboratory parameters were examined. Results: Total 1200 patients with urolithiasis were divided into two groups (with [n = 208] and without metabolic syndrome [n = 992]). The mean age of total population was 47.26 (14.68) years with 721 males and 479 females. The mean height, weight, BMI were significantly different between both groups (P < 0.001). Proportion of obese (BMI >25) patients, proportion of patients with hyperuricemia, waist circumference, blood pressure, triglyceride, fasting blood sugar (FBS) levels were significantly higher in patients with metabolic syndrome; however, high density lipoprotein (HDL) levels were significantly reduced in metabolic syndrome group (P < 0.001). A significantly increasing trend in mean waist circumference, triglycerides, FBS, systolic blood pressure and diastolic blood pressure and a decreasing trend in mean HDL with increase in number of metabolic components were observed (P < 0.001). Female patients were 19.6 times more likely to develop metabolic syndrome than male patients (P < 0.001). Increasing waist circumference, triglycerides, FBS, blood pressure were associated with increased risk of metabolic syndrome (P < 0.05). Decreasing HDL was associated with reduced risk of metabolic syndrome. Patients with hyperuricemia were 5.68 times more likely to exhibit metabolic syndrome (P = 0.006). Conclusion: This study indicates the presence of a significant association of metabolic syndrome and its components with urolithiasis.


How to cite this article:
Rams K, Philipraj S J, Purwar R, Reddy B. Correlation of metabolic syndrome and urolithiasis: A prospective cross-sectional study.Urol Ann 2020;12:144-149


How to cite this URL:
Rams K, Philipraj S J, Purwar R, Reddy B. Correlation of metabolic syndrome and urolithiasis: A prospective cross-sectional study. Urol Ann [serial online] 2020 [cited 2022 Jan 24 ];12:144-149
Available from: https://www.urologyannals.com/article.asp?issn=0974-7796;year=2020;volume=12;issue=2;spage=144;epage=149;aulast=Rams;type=0